Lucie Y. Guo, MD, PhD

Lucie Y. Guo, MD, PhD is a tenure-track Assistant Professor of Ophthalmology at the Perelman School of Medicine of the University of Pennsylvania. Dr. Guo received her B.A. in Biochemical Sciences from Harvard, where she graduated magna cum laude. She completed her MD and PhD at the University of Pennsylvania; she conducted thesis research with Dr. Ben Black on chromatin epigenetics through the Biochemistry Biophysics Chemical Biology graduate group. She graduated with multiple awards including Alpha Omega Alpha, the Saul Winegrad award for outstanding dissertation, the Charles A. Oliver Memorial Prize in Ophthalmology, and the Jeffrey Berger Medical Student Award in Ophthalmology. She completed Ophthalmology Residency and Vitreoretinal Surgery fellowship at Stanford University, where she did postdoctoral fellowship with Dr. Stanley Qi in the Department of Bioengineering at Stanford on genome engineering for ophthalmic gene therapy. She was awarded the Fellow Teaching Award at Stanford, as well as the Ron Michels Fellowship Award in Retina. In 2025, she received the NIH Director’s Award for Early Independence (DP5) for launching her laboratory. She joined Penn faculty in September 2025.